Sunday, 1 September 2019

CGHS Pharmacist Solved Questions Paper 2018 -19

1.Which of the following is not among the ORPHAN DRUG'S
B. Ketocanazole
C. Liposomal amphotericin B √
D. Sodium Nitrite

2. Pharmacy Act Passed
A. 1965
B. 1985
C. 1948 √
D. 1950

3. Which of following produces VASOCONSTRICTION as the most prominent action
A. Angiotensin-II √
B. Fenoldopam
C. Sodium Nitroprusside
D. Nicardipine

4. The normal range of HDL Cholesterol in a male is
A.120 to 140 mg/dl
B. 30 to 60 mg/dl
C. 160 to 200 mg/dl
D. 40 to 60 mg/dl√

5. BLOOD GROUP ANTIGEN belong which of the following class of protein
B. Lipoprotein
C. Glycoprotein√
D. Nucleoprotein

6. Thyroid stimulating hormone(TSH) or thyrotropic hormone is secreted by which gland
B. Posterior Pituitary
C. Anterior Pituitary√
D. Supra renal

7. For the management of Asthamatic Cough, which of following is right treatment approach
A.H2 blocker
B. Antibiotics
C. Proton pump inhibitor
D. Inhaled beta 2 agonists√

8. The recommended daily allowance of “Vitamin A” for women is
A.50 mcg/day
B. 750 mcg/day√
C. 450 mcg/day
D. 250 mcg/day

9. Among the following Antidepressant Phychotropic drugs,  which one belong to the classification of “Monoamine oxidase inhibitors”
B. Fluoxetine
C. Tranylcypromine√
D.  Amphetamines

10. The normal rhythmical impulse is generated from which point in the conductive system of heart
A.Atrioventricular Bundle
B. Sinoatrial Node√
C. Purkinje Fiber
D. Atrioventricular Node

11. Which of the following is Cholinergic Blocking agent
B. Acetylcholine
C. Atropine√
D. Pilocarpine

12. Which of the following enzymes is markedly increase in “Obstructive Liver Disease”
A.Creatine kinase
B. Alanine Aminotransferase
C. Alkaline Phosphatase√
D. Asparate Aminotransferase

13. Which of the following is POTASSIUM SPARING DIURETIC
B. Isosorbide
C. Mannitol
D. Glycerol

14. Which of the following chamber of heart receives venous blood from the whole body
A.Right Ventricle
B. Right Atrium√
C. Left Ventricle
D. Left Atrium

15. What is the penalty for 'commercial quantity sale’ of Drug's that cause dependence or Abuse
A.Rigorous Imprisonment for 10 to 20 year + fine of ₹ 1 to 2 lakh√
B.Rigorous Imprisonment for 4 to 6 year + fine of ₹ 50,000 to 60,000
C. Rigorous Imprisonment for 1 to 2 year + fine of ₹ 10,000 to 20,000
D. Rigorous Imprisonment for 5 to 6 year + fine of ₹ 3 to 4 lakh

16. Which of the following is the largest tarsal bone
B. Calcaneus√
C. Cuboid
D. Talus

17.The route of administration of human monovalent live vaccine (RV1) for Rotavirus is
B. Oral√
C. Intra Muscular
D. Intra-dermal

18. At what temperature 'the short and medium chain fatty acids’ are SOLIDS
B. 15 
C. 25 

19. Which one of the following is not a salient feature of a Hospital Pharmacy
A.Supply of Pharmaceutical Drugs
B. Dispensing of Narcotic Products
C. Design of a New Drug√
D. Supply and storage of ancillary product

20. The HYDROCHLORIC ACID in stomach is secreted by which type of cells
A.Mucus neck cells
B. Enterochromaffin cells
C. Pariental cells√
D. Enterochromaffin like cells

21. Which of the following can be used as an antidote for Atropine
B. Oxyphenonium
C. Hyocine butyl bromide
D. Physiostigmine√

22. Which of the following is a Heteroglycan
B. Glycogen
C. Cellulose
D. Hyaluronic acid√

23. Which of the following is a LIPOLYTIC ENZYME
B. Nuclease
C. Cholesterol ester hydrolase√

24. What is the  fatal dose of Antihistamines
A.1 to 5 mg/kg
B. 5 to 10 mg/kg
C. 10 to 15 mg/kg
D. 25 to 50 mg/kg√

25. All of the below are sources of Vitamin E, EXCEPT
A.Wheat germ oil
B. Sunflower oil
C. Fish liver oil√
D. Cotton seed oil

26. Which of the following is in the normal range of weight of the right Lung in an adult
A.1175 gm
B. 120 gm
C. 625 gm√
D. 1345 gm

27. Which of the following is primary site of action of local anesthetic
B. Cytoplasm
C. Nucleus
D. Cell Membrane√

28. Which of the following food source has the highest 'Mean Iodine content’
B. Vegetables
C. Fresh water Fish
D. Sea water Fish√

29. What of the following drug acts as a Mucolytic
B. Chlorpheniramine
C. Salbutamol
D. Codeine

30. DNA Replication and Transcription is the function of which subcellular organelle
A.Endoplasmic Reticulum
B. Nucleus√
C. Golgi body
D. Lysosome

31. What is the maintenance dose of Roxatidine
A.150 mg twice a day
B. 75 mg at Bed time√
C. 150 mg Three times a day
D. 75 mg Three times a day

32. The route of administration of vaccine BCG is
B. Intra-muscular
C. Intra-dermal√
D. Intravenous

33. Which of following is not a lipid derived autacoids
B. Prostaglandins
C. Histamine√
D. Platelet activating factor

34. Which of the following is an example of AROMATIC AMINO ACIDS
B. Theonine
C. Glutamine
D. Tyrosine√

35. Among the peripherally acting muscle relaxants, which of following is a DEPOLARIZING BLOCKER
B. Pipecuronium
C. Suxamethonium√
D. Atracurium

36. METHADONE help in recovery of which of the following type of Drugs dependence
A.Morphine type√
B. Cocaine type
C. Cannabis type
D. Amphetamine type

37. The group of enzyme which can hydrolase ester, ether, peptide or glycosidic bond by adding water and then braking the bond is __
B. Transferases
C. Hydrolases√
D. Oxyreductases

38. Which of the following symptoms is not specific of DRUGS HABITUATION
A.Tendency to Increase the drug dose√
B. Has desire for drug but no compulsions
C. No tendency to Increase the drug dose
D. None or mild drug withdrawal symptoms

39. In utilization of finance, the ‘Fixed Capital’ is invested on which of the following
A.Purchase of raw materials
B. Wages and rent
C. Plant and machinery√
D. Taxes and internet

40. “Varicella vaccine” is given for the prevention of which of following Disease
A.Chicken pox√
B. Cervical cancer
C. Hepatitis A
D. Tuberculosis

41. How many coccygeal vertebrae fuse to from coccyx bone
B. 6
C. 8
D. 2

42. Which of following CNS depressant Barbiturates is long acting
A. Barbitone√
B. Thiamylal sodium
C. Pentothal sodium
D. Cyclobarbital

43. When PARASYMPATHETIC STIMULATING drugs are used, which of the following action on heart is noted
B. Conductivity is enhance
C. Tachycardia
D. Refractory period of atria is shortened

44. What is Chemical formula of Acetic Acid

45. Conjunctival Xerosis occurs due to deficiency which of the following Vitamins
A.Vitamin A√
B. Vitamin B
C. Vitamin C
D. Vitamin K

46. What is the name of ‘type of drug administration’ in which of the drug is deposited in the loose tissue under the skin which is richly supplied by nerves but is less vascular
B. Subcutaneous√
C. Intrathecal
D. Intra-dermal

47. What is the dose of Hepatitis B for children under 10 years of age
A.0.5 ml√
B. 1.5 ml
C. 1 ml
D. 2 ml

48. What is paralytic dose of paraldehyde
A.25 to 50 ml √
B. 5 to 10 ml
C. 10 to 15 ml
D. 15 to 20 ml

49. Which of the following cytotoxic medicines used in chemotherapy is an antimetabolite
B. Mechlorethamine
C. Isophosphamide
D. Cyclophosphamide

50. The 'Shop Work License' issued by the Labor Office is valid for how many years from the date of its expiry
A.3 year√
B. 5 year
C. 4 year
D. 2 year